You do not need me to solve this puzzle, but here is the solution.
tRNA evolved from: GCG, CGC, UAGCC repeats and stem-loop-stems (~CCGGG_CU/???AA_CCCGG).
4 points:
The initial sequence was completely ordered: RNA repeats and inverted repeats (stem-loop-stems).
The anticodon and T stem-loop-stems were initially identical.
tRNA evolved from ligation of three 31 nucleotide minihelices of known sequence.
Type I and type II tRNAs evolved by very similar mechanisms. An early version of type II tRNA could be processed to type I tRNA. The type I V loop was processed from the type II V loop by a known 9 nucleotide deletion. The 9 nucleotide deletion in the D loop region (within ligated 3’- and 5’-acceptor stems) was identical to the V loop 9 nucleotide deletion, on the complementary strand.
Once tRNA evolves, life evolves.
tRNA was the molecule that taught itself (with friends) to code.
Anyone out there who likes working puzzles?
This isn’t even a difficult one.
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